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MCQ on Regulation of Gene Expression in Eukaryotes

Let’s review the fundamentals of genes before moving on to gene expression and control. As a result, you’ll be better equipped to grasp the principles discussed above and study more about relevant topics with ease.

Genes are the functional units of DNA, which serve as the cell’s information database and are located in the nucleus. Genes carry all genetic instructions or genomes that make proteins.

Now, each of these genes carries a unique set of instructions, most of which are stored in a coded fashion. This instruction is frequently utilised to accurately conduct a specific function towards a specific protein.

These genes are replicated into mRNA and then converted into a chain of polypeptides, which aids in the development of distinctive features or gene expression.

What is Gene Expression and How Does It Work?

It is the mechanism in which genomes are employed to control protein production. The body uses the protein that has been synthesised to make cell structures. It’s also a well-coordinated process that allows cells to respond to changes in their surroundings.

It’s worth noting that structural genes are those that provide information about how to utilise amino acids. Furthermore, there are two separate processes in this procedure.

Transcription

RNA is synthesised with the help of RNA polymerase enzymes in this step. As a result, the mRNA molecules undergo processing

Translation

This stage is more focused with mRNA-mediated protein synthesis. The processing of protein molecules begins during the course of activity.

Thus, in simple terms, it is the process by which DNA instructions are converted into a usable product, which in this case is a protein.

What is Gene Expression Regulation?

It’s the method through which cells can control when and how gene expression is regulated. However, this regulation is highly complex, and any malfunctioning can be harmful to cells, resulting in the onset of a variety of disorders, including cancer.

Gene expression regulation typically aids in the conservation of space and energy. It also allows living organisms to adapt to changes in their environment

Furthermore, it is common for each cell to have a varied set of activated genes that facilitate different activities. For example, liver cells are in charge of eliminating toxins from the bloodstream, whereas neurons are in charge of signal transmission.

On that topic, let’s have a look at the significance of gene regulation in the following sections!

Gene Regulation’s Importance

Gene expression and control are thought to be important for –

a) Growth

b) Development

c) Existence

d) Differentiation

  1. Eukaryotic entities 

(a) carry out protein synthesis in the presence of the cAMP molecule 

(b) contain just operons that help with gene expression.

(c) Transcription occurs in the nucleus, while translation occurs in the cytoplasm.

cytoplasm

(d) Transcription takes place in the cytoplasm, while translation takes place in the nucleus.

The answer is: (c)

  1. A genomic DNA molecule contains functional units, which are a collection of genes.

genes that are influenced by promoters are referred to as

a) Genetics

b) operons 

c) anticodon 

d) codon

The answer is: (b)

  1. All regulatory proteins share a DNA-binding domain.

feature in their protein chains that is particular flexees

allowing them to interact with each other

a) the DNA helix’s outer groove

b) the DNA helix’s main groove

c) the DNA helix’s minor groove

d) DNA helix inner groove

The answer is: (b)

  1. Transcription is turned off by regulatory proteins.

binding to a location at the promoter’s front quickly and

This site, which frequently overlaps the promoter, is the

a) a regulatory authority

b) the operator’s location

c) suppressor location

d) a transcriptional checkpoint

The answer is: (b)

  1. There appears to be a protein in vertebrate cells that

interacts to 5-methylcytosine clusters, guaranteeing that the

The bound gene remains in the “off” state. This rule relates to

The function of gene regulation is a result of

a) Methylation 

b) Interpretation

d) Expression of enhancers

c) suppression of the operator

The answer is: (a)

  1. In eukaryotes, transcriptional gene control is

mediated through

a) metabolites that bind to cis-acting elements

b) failure of trans-acting factors to bind to cis-acting elements

c) binding of trans-acting factors to cis-acting components

(d) proteins that attach to operator sites and act as repressors

The answer is: (c)

  1. One of the most basic instruments for genetic control is the ability of some genes to regulate each other.

proteins that bind to particular molecules

a) DNA sequences that regulate gene expression

b) RNA regulatory sequences 

c) cellular enzymes

(d) gene promoter portions

The answer is: (a)

This is an inaccurate statement in the regulation of gene expression.

statement

a) In bacteria, it allows for unrestricted replication.

b) It allows bacteria to adapt to changing surroundings.

Multicellular entities 

(c) allow for the maintenance of homeostasis.

d) allows multicellular creatures to function as a whole.

The answer is: (a)

In the centre of a cell, there are this many histones.

nucleosome

a) 8 

b) 6  

c) 4 

d) 2 

The answer is: (a)

The most frequent type is in eukaryotes and bacteria.

It is necessary to regulate.

a) regulation of the promoter

b) regulation of translation

c) regulation of the repressor

d) transcriptional regulation

The answer is: (d)

11.One of the most basic instruments for genetic control is the ability of some genes to regulate each other.

proteins that bind to particular molecules

a) DNA sequences that regulate gene expression

b)RNA regulatory sequences 

c) cellular enzymes

d) gene promoter portions

The answer is: option (a) 

12.In eukaryotes, transcriptional gene control is

mediated through

a) metabolites that bind to cis-acting elements

b) failure of trans-acting factors to bind to cis-acting elements

c) binding of trans-acting factors to cis-acting components

d) proteins that attach to operator sites and act as repressors

The answer is: option c)