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NEET UG 2026 » NEET UG Study Material » Biology » Cholesterol
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Cholesterol

to understand cholesterol, the physiology of cholesterol, the function of cholesterol, and types of cholesterol

Table of Content
  •  

Cholesterol is a lipid that’s either a fat or a fat-like molecule. It is soft and waxy in nature. Cholesterol is a steroid lipid. Steroids are a type of lipid with a unique chemical structure. The structure is composed of four carbon atom rings. Cholesterol is found only in animal cells. The body needs some amount of cholesterol to keep the cell and organs healthy. Animals produce some steroids, which are hormones and cholesterol. Cholesterol is also important in the production of vitamin D and hormones. The discoverer of cholesterol is François Poulletier de la Salle, who identified it in 1769. Cholesterol is not found in prokaryotic organisms, except mycoplasma.

Physiology of cholesterol

Cholesterol is necessary for all animal lives. It is produced by each cell of the animal body. The rate in steps to produce cholesterol. An adult male produces one gram of cholesterol every day. Plants can also reduce cholesterol in very minute quantities; instead of cholesterol, phytosterol is produced by plants. They are chemically similar.

The functions of cholesterol

  • 1/3 of the cell membrane of animals is composed of cholesterol. Cholesterol is needed to make and maintain membranes and membrane fluidity.
  • It acts as a precursor for the formation of essential compounds for the body, such as the steroid hormones progesterone and testosterone, vitamin D, and bile acids.
  • It regulates the biological process of substrate presentation. A substrate presentation is a process to activate proteins.
  • Cholesterol is also needed in the process of cell signalling.
  • Cholesterol with phospholipid acts as our electrical insulator and functions in the transmission of electrical impulses.
  • It serves as a precursor molecule in a number of metabolic processes.

Types of cholesterol

There are 3 types of cholesterol on the basis of its carrier, lipoprotein:

  1. Low-density lipoprotein or LDL – It is also known as bad cholesterol. LDL can accumulate on the lining of your arteries, narrowing them. The fatty deposits harden into plaque, which can block your arteries. Atherosclerosis is the name for this build-up. We shouldn’t eat food with LDL cholesterol or saturated or trans-fat.
  1. High-density lipoprotein or HDL – It is known as good cholesterol. It’s good because it takes away low-density cholesterol from your arteries. It is like a dumping mechanism that removes bad cholesterol from the body, transfers it to the liver, and reduces the risk of heart disease.
  1. Very low-density lipoprotein or VLDL – It transports triglycerides from the intestine and liver to capillary beds in muscle and adipose tissue. It is hydrolysed into fatty acids there and can be oxidised to form adenosine triphosphate (ATP) for energy production.

Conclusion

Cholesterol is a type of lipid. It is basically a steroid that is yellowish waxy and soft in nature that generates cholesterol in the body. The chemical structure of cholesterol is complex. Cholesterol is needed to perform any function of the cell in the animal body. It is not present in plant cells. But high cholesterol levels can cause many diseases because cholesterol builds up in the arteries and blocks the flow of blood, which can cause a heart attack. So it is necessary to maintain cholesterol. We should avoid high cholesterol food for good health. The causes of high cholesterol are smoking, obesity, lack of exercise, and a diet with high saturated fat.

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Frequently asked questions

Get answers to the most common queries related to the NEET Examination Preparation.

What is cholesterol?

Cholesterol is a soft wax-like lipid sterol. It is synthesised in animal cells and is a necessary component for the ...Read full

What is the difference between good cholesterol and bad cholesterol?

Low-density lipoprotein or LDL is called bad cholesterol and high-density lipoprotein or HDL is called good choleste...Read full

What are the diseases caused by high cholesterol?

The diseases caused by high cholesterol are heart stroke, peripheral arterial diseases, diabetes, high blood pressur...Read full

What are the reasons for high cholesterol in the body?

The factors which lead to high cholesterol are: If your family has a hi...Read full

Write some histone modification processes?

The structure of cholesterol consists of 27 carbon compounds with a hydrocarbon tail, a sterol nucleus made up of 4 ...Read full

What are the properties of cholesterol?

Cholesterol combines with fatty acid chains of phospholipids to modify membrane characteristics. Cholesterol immobil...Read full

Cholesterol is a soft wax-like lipid sterol. It is synthesised in animal cells and is a necessary component for the cell membrane. It is also necessary for the synthesis of hormones and vitamin D and steroids. A high amount can cause heart risks.

Low-density lipoprotein or LDL is called bad cholesterol and high-density lipoprotein or HDL is called good cholesterol. The LDL takes the cholesterol from the liver to the body, which increases the amount of cholesterol in the body. HDL is good cholesterol because it carries cholesterol from the body to the liver, where the cholesterol can break down and convert into energy.

The diseases caused by high cholesterol are heart stroke, peripheral arterial diseases, diabetes, high blood pressure, and coronary heart diseases.

The factors which lead to high cholesterol are:

If your family has a history of high cholesterol, then there is a chance that you can also have it.

Saturated and trans-fat-rich food increases the level of cholesterol in the body.

Being overweight increases the level of LDL cholesterol in the body.

The structure of cholesterol consists of 27 carbon compounds with a hydrocarbon tail, a sterol nucleus made up of 4 hydrocarbon chains in the centre, and a hydroxyl group.

Cholesterol combines with fatty acid chains of phospholipids to modify membrane characteristics. Cholesterol immobilises the membrane’s outer surface, limiting fluidity. It maintains the permeability of the membrane to very small polar molecules.

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