Amniocentesis

Amniocentesis is a diagnostic procedure that is performed during a pregnancy to determine the health of the baby. It is most commonly used to examine the chromosomes of a newborn baby. In some cases, amniocentesis is performed to examine diseases that can occur during pregnancy, such as infections or genetic disorders. This procedure involves the removal of amniotic fluid from the womb. Most of the time, a local anaesthetic is not required.

In addition to the amniotic fluid, which contains foetal cells as well as other substances such as alpha-fetoprotein, the foetus also has a sac surrounding it. It also serves to protect the foetus from any mechanical injury and to aid in the regulation of the foetus’s body temperature. Before birth, the amniotic fluid contains cells and substances that provide important information about the health of the unborn child and the mother.

What is the reason for this?

Amniocentesis can be performed for a variety of reasons, including:

• Genetic testing is a procedure that is used to determine a person’s genetic makeup. It is possible to obtain a sample of amniotic fluid and have it tested for certain conditions, such as Down syndrome, during a genetic amniocentesis.
• Testing of the fetus’s lungs. An amniotic fluid sample is taken and tested to determine whether or not a baby’s lungs are mature enough to be delivered at the time of birth.
• Identifying the presence of foetal infection. Amniocentesis is a procedure that is occasionally used to evaluate a baby for infection or other illness. Another application for this technique is assessing anaemia in newborns who have Rh sensitisation, a rare condition in which the mother’s immune system produces antibodies against a specific protein on the surface of her child’s blood cells.
• If a person accumulates an excessive amount of amniotic fluid during pregnancy (polyhydramnios), you may need to have an amniocentesis procedure performed to drain the excess amniotic fluid from your uterus.
• Testing for paternity. Amniocentesis is a procedure that collects DNA from a foetus, which can then be compared to DNA from the prospective father.

Procedure of Amniocentesis

The following is the procedure for performing an amniocentesis:

• The patient is instructed to lie down on the table and to place his or her hands behind his or her back.
• The patient’s blood pressure, heart rate, and respiration rate are all measured.
• An ultrasound is used to check the heart rate of the foetus, the position of the placenta, the position of the foetus, the position of the umbilical cord, and the location of the pocket of amniotic fluid.
• The abdomen is cleansed with an antiseptic solution before an anaesthetic is administered.
• To collect the amniotic fluid, a long, thin, hollow needle is inserted into the uterus and left there for several minutes.
• The fluid that has been collected is placed in a container that is protected from light.
• The heart rates of both the foetus and the patient are checked again and compared.
• The fluid that has been collected is sent to a laboratory for examination.

Ban on Amniocentesis

The practice of amniocentesis was outlawed in India in 1994 under the “Preconception and Prenatal Diagnostic Techniques Act” of that country. This was done because amniocentesis had the potential to reveal the gender of the foetus. Given that having a girl child is not accepted in many parts of the country, the female foetus is aborted in the vast majority of cases. To prevent this from happening, amniocentesis was outlawed in India.

Risks

Amniocentesis entails several risks, including the following:

• Amniotic fluid may leak after an amniocentesis. However, in the majority of cases, the amount of fluid lost is minimal and ceases within a week, and the pregnancy is likely to proceed normally after that.
• According to research, amniocentesis performed before 15 weeks of pregnancy is associated with a higher risk of miscarriage than after that time.
• Injury caused by a needle. During amniocentesis, the baby may move an arm or a leg into the path of the needle, which could cause complications. Serious needle injuries, on the other hand, are extremely rare.
• Sensitization to the Rh factor. Amniocentesis may cause the baby’s blood cells to enter the mother’s bloodstream in rare cases. During amniocentesis, if you have Rh-negative blood and have not yet developed antibodies to Rh-positive blood, you will be given an injection of a blood product known as Rh immune globulin, which is a type of plasma product. In this way, your body will be prevented from producing Rh antibodies, which can cross the placenta and cause damage to your baby’s red blood cells during pregnancy. A blood test can tell you whether or not your body has begun to produce antibodies.
• Uterine infection can occur as a result of amniocentesis in a very small number of cases.
• Transmission of an infection. Amniocentesis may result in the transmission of a contagious infection to your baby if you have a virus such as hepatitis C, toxoplasmosis, or HIV/AIDS.

Conclusion

Amniocentesis is a procedure in which amniotic fluid is removed from the uterus for testing or treating the mother or child. It is the fluid that surrounds and protects a baby during pregnancy that is referred to as amniotic fluid. This fluid contains foetal cells as well as several different proteins. When a foetus (developing baby) is enclosed in amniotic fluid, the fluid contains cells and chemicals that can provide information about the foetus’s health.