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UPSC » UPSC CSE Study Materials » NCERT Notes for UPSC 2025 » Disease

Disease

Classification of Disease, Infectious Diseases, Immune System, Disease and its Causes.

Table of Content
  •  

Health is a nation of being properly sufficient to characterise properly physically, mentally, and socially. The fitness of all organisms relies upon their environment or their surroundings. The surroundings consist of the bodily surroundings. Social equality and concord also are vital for character fitness.

Disease and its Causes

A disease refers to any illness that compromises one’s health or interferes with the body’s regular functioning. When there’s an ailment, the functioning of 1 or extra structures of the frame will alternate for the worse. These modifications supply upward thrust to signs and symptoms and symptoms and symptoms of an ailment.

  • Symptoms: These are the matters which can be felt as being ‘wrong’ together with Headache, cough, free motions
  • Signs: Signs of ailment are what physicians will search for primarily based totally on the signs and symptoms
  • These supply a touch an extra exact indication of the presence of a selected ailment

Classification of Disease: 

Depending on their duration, Diseases are classified as acute or chronic:

  • Acute illnesses: These sicknesses close for the simplest very quick intervals of time together with cold
  • Chronic illnesses: It is a human fitness circumstance or ailment this is continual or in any other case long-lasting in its outcomes together with Tuberculosis

Causes of Disease:

 Immediate causes of disease belong to two distinct types:

  • Infectious illnesses: These illnesses are resulting from infectious retailers together with microbes or microorganisms
  • For example, Tuberculosis is resulting from Bacteria
  • These retailers can unfold within the network and the illnesses they purpose additionally unfold with them
  • Non-infectious illnesses: These illnesses are resulting from mainly internal, non-infectious reasons
  • For example, Cancers are resulting from genetic abnormalities
  • High blood stress is an end result of immoderate weight and the absence of exercise

Infectious Diseases

  • Infectious retailers: They belong to specific classes of organisms and can be unicellular and microscopic or multicellular
  • Microscopic: Viruses, bacteria, fungi
  • Unicellular: Protozoans
  • Multicellular: Worms of various kinds

Table 13.1: Infectious agents and related diseases

Infectious agents

Related Diseases

Viruses

Common Cold, Influenza, Dengue fever, AIDS

Bacteria

Typhoid fever, Cholera, Tuberculosis, Anthrax

Fungi

Common Skin Infections

Protozoan

Malaria and Kala-azar

Worm

Intestinal infections, Elephantiasis

Means of Spread:

Many microbial retailers can pass from an affected character to a person else through the air, water, bodily touch, or vectors. Such illnesses which may be communicated in this manner are referred to as communicable illnesses.

Common methods of transmission of diseases:

  • Air: This takes place through the little droplets thrown out through an inflamed character whilst sneezing or coughing
  • Someone status close-through can breathe in those droplets, and the microbes get a danger to begin brand new contamination.
  • Examples: Common cold, Pneumonia and Tuberculosis
  • The more crowded our living conditions become, the more likely it is that such airborne illnesses will unfold
  • Water: This takes place if the excreta from a person tormented by an infectious ailment get combined with the ingesting water utilized by human beings residing nearby
  • Cholera inflicting microbes input a wholesome character thru the water they drink and the purpose ailment in them
  • Such illnesses are more likely to unfold in the absence of secure elements of ingesting water
  • Physical Contact: This consists of sexual acts and informal bodily contact (together with handshakes or hugs or sports, like wrestling)
  • Microbial infections together with syphilis or AIDS can be transmitted through sexual touch from one accomplice to the different

Reasons why HIV AIDS unfold

  • Blood-to-blood touch with infected human beings
  • An infected mom to her toddler for the duration of being pregnant or through breastfeeding
  • Vector: These are animals which act as intermediaries and convey the infecting retailers from an unwell character to any other ability host The not unusual place vectors are mosquitoes
  • In many species of mosquitoes, the girls want especially nutritious meals in the shape of blood to put mature eggs
  • Mosquitoes feed on many warm-blooded animals (like humans) and switch sicknesses from character to character

Organ-specific and Tissue-specific manifestations:

The ailment-inflicting microbes input the frame through those specific methods after which visit unique organs or tissues to act. This choice can be related to:

Entry body part

  • Enter through the nose: Go to lungs like tuberculosis inflicting bacteria
  • Enter through the mouth:
    • Stay in the intestine lining like typhoid inflicting bacteria
    • Go to the liver, like jaundice inflicting viruses

Other modes:

  • HIV Virus: Comes into the frame thru the sexual organs and unfolds to lymph nodes everywhere in the frame
  • Malaria-inflicting microbes: Enter through a mosquito chunk and visit the liver, after which to the Red Blood Cells (RBC)
  • Japanese encephalitis (mind fever) inflicting virus: Enter through a mosquito chunk and is going directly to infect the mind

Thus, the signs and symptoms of an ailment depend upon the tissue or organ that the microbe targets.

  • If the lungs are the targets, then signs and symptoms may be cough and breathlessness
  • If the liver is targeted, there may be jaundice
  • If the mind is the target, there may be headaches, vomiting, suits or unconsciousness

Immune System:

In addition to those tissue-unique outcomes of infectious ailment, there may be different not unusual place outcomes which depend on the frame’s immune device and were activated in reaction to contamination.

  • An energetic immune device recruits many cells to the affected tissue to kill off the ailment-inflicting microbes
  • This recruitment system is referred to as inflammation
  • As part of this system, there are nearby outcomes together with swelling and pain, and fashionable outcomes together with fever
  • In a few cases, the tissue-specificity of the contamination ends in very fashionable-seeming outcomes

For example

  • In HIV contamination, the virus goes to the immune device and damages its characteristics
  • Minor intestine contamination can produce fundamental diarrhoea with blood loss

The severity of ailment: It relies upon the number of microbes within the frame.

  • If the number of microbes could be very small, the ailment manifestations can be minor or unnoticed
  • If the quantity is of the identical microbe large, the ailment may be intense enough to be life-threatening
  • The immune device is a first-rate issue that determines the number of microbes surviving within the frame

Conclusion

We looked into what a disease is, what are its types, as well as the common factors in the spread of diseases. We can hence state that diseases are often seen as medical disorders distinguished by their signs and symptoms. The sickness may also be described as “any harmful deviation from an entity’s functioning or normal condition.” Disease refers to any illness that compromises one’s health or interferes with the body’s regular functioning. And, immunisation is the process of administering (injecting) vaccines into a healthy individual in order to create immunity against a disease.

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