A Simple Note on Reimer Tiemann Reaction Mechanism

The Reimer Tiemann reaction is an organic chemical reaction used to convert phenol into o-hydroxy benzaldehyde by using chloroform which is an acid-based component. This chemical reaction is identified by the name of scientists Karl Reimer and Ferdinand Tiemann. The reaction type of the identified reaction process is an electrophilic substitution reaction as it is used for the ortho-formulation phenols and acts for dichlorocarbene as the base of electrophile. This process is known for the ester of phenol yields as the phenolic ketones are used in the Reimer-Tiemann reaction with the anhydrous aluminum chloride to represent para hydroxy acetophenones.

The Reimer Tiemann Reaction as an Organic Chemical Reaction

The Reimer Tiemann reaction is an organic chemical reaction that is used for conducting reactions related to ortho-formylation of phenols. The reaction process of the ortho-formylation of phenols indicates the changes in the presence of sodium hydroxide at the time when phenol is treated with the involvement of chloroform (CHCl3) used in the Reimer-Tiemann reaction. Through this process the -CHO group is represented as ortho positioning that also represents the benzene ring. The reason behind calling the Reimer Tiemann reaction is an organic chemical reaction is because of the presence of chloroform as the base of NaOH/KOH and comprises an aldehyde or -CHO that introduces to the position of the ortho to the phenolic group and the formation of the salicylaldehyde.

Explanation of the Mechanism of Reimer Tiemann Reaction

The reaction is related to the reaction and has correlated with multiple mechanisms. The Reimer Tiemann reaction is an organic chemical reaction so the process is defined by the positions of the phenolic group. The process helps to identify the collaborative format of positioning the ortho phenolic group in the presence of the benzene ring and the reaction takes place as the process leads to the growth of salicylaldehyde in the reaction process. The main element that gets produced in this reaction process is an aldehyde. The mechanism of the Reimer Tiemann reaction is related to the deprotonation of the normal distribution of the hydroxide. This process develops chloroform carbanion. After that, the process of alpha-eliminates and dichlorocarbene is produced. This is produced by maintaining the principles related to the reactive species and also engages the deprotonate phenol with the negatively charged phenoxide. After this situation in the chemical reaction, the negative charge delocalized the ring which is known as the aromatic ring. This process makes the reaction more nucleophilic and the attack of the elements on dichlorocarbene decides the intermediate substitute of dichloromethyl by phenol. After the conduction of these mechanisms, the reaction leads to the release of basic hydrolysis and the desired element by the intervention of the reactions.

Reagents Used in Reimer-Tiemann Reaction

The process of the reaction is only conducted based on the reaction conditions that are very specific and ideal to present the required product with the reaction. The hydroxides used in the Reimer-Tiemann reaction are not properly soluble in the chloroform thus the reaction can be conducted in the biphasic system which is also a solvent process considered for containing chloroform. In this situation, the two reagents used for the reaction purpose are phenols and salicylaldehyde.

Conclusion

The process of reaction is related to chemicals that are used for reacting with the ortho-formylation which is the conversion of phenol to salicylaldehyde. The Reimer Tiemann reaction is an organic chemical reaction because the conversion process does not need any outer influence to simplify and the outcome is comprehensively managed to discover the mechanism of the chloroform carbanion. This involves phenol and chloroform in the presence of an alkali and majorly NaOH. The process is related to the conversion of phenol that is becoming o-hydroxy benzaldehyde by the influence of chloroform. Mainly is the reaction the acid-based element is working as the primary element