Dr Praveen Kumar Agrawal is teaching live on Unacademy Plus
COURSE BIOMOLECULES Lesson Structure of RNA Dr. Praveen Kumar Agrawal
Structure of RNA RNA consists of single polynucleotide chain and therefore it G exists as single strand. This polynucleotide chain consists of ribonucleotides Ribonucleotides contain ribose sugar, a phosphate radical and one nitrogenous base. The nitrogenous bases present in RNA nucleotides are Adenine, @ Guanine, Cytosine and Uracil (Thymine is absent, instead there is presen t uracil) RNA nucleotides are also of four types. RNA does not follow Chargaff's rule. It's guanine contents are not necessarily equal to its cytosin e contents and similarly its adenine contents are not necessarily equal to its uracil contents. Various ribonucleotides in RNA are also joined together b Phosphodiester bonds to form polynucleotide chain. . RNA strand has well defined ends. One is 3' while other is 5'.
Differences between DNA and RNA Properties DNA RNA Type of pentose sugar Nitrogenous base thymine No. of polynucleotide chains Twisting Purine to pyrimidine ratio Chargaff rule Mol. Wt Length Function Formation Deoxyribose Thymine is present Two (double helical) Present One Follows Chargaff rules Very high Very long As genetic material in all organisms By self replication Ribose Thymine is absent. Instead Uracil is present One Usually absent Any Does not follow Comparatively low Shorter As genetic material only in RNA and retro viruses By transcription (from DNA)
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