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Structure of DNA
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Dr Praveen Kumar Agrawal is teaching live on Unacademy Plus

Dr Praveen Kumar Agrawal
Ex - Faculty, Allen Kota, 22 Yrs Experience. Author - 17 books Known for best explanation Youtube : biology by pkagrawal

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  1. COURSE BIOMOLECULES Lesson Structure and DNA double helix Dr. Praveen Kumar Agrawal


  2. Formation of a nucleotide NH2 - POHH Phosphate H Deoxyribose -2 H2O ta-N-Glycosidic HH Phospho-ester bond


  3. Four types of nucleotides (1) Nucleotide with nitrogenous base - Adenine (2) Nucleotide with nitrogenous base - Thymine (3) Nucleotide with nitrogenous base - Cytosine (4) Nucleotide with nitrogenous base Guanine Adenine Thymine Cytosine Guanine


  4. Structure of a nucleotide NH2 HO CH2-O OH A Deoxy-ribonucleotide


  5. Joining of nucleotides and phosphodiester bond NH2 NH2 HO CH2 O OH CH2 O OH H/ H Nucleotide Phospho- diester bond NH2 NH2 Nucleotide Dinucleotide


  6. 5 3' 3' 5 Opposite Polynucleotide chains


  7. Chargaff Base pairing rule a Each base will only bond with one other specific base. n A with T A is always equal to T C is always equal to G So, in a DNA sample, Purine Is always equal to pyrimidine Cwith G Adenine (A) Form a base pair Thymine (T) Cytosine (C) Guanine (G) Form a base pair There are double bond between A and T. But there are triple bonds between C and G


  8. DNA Structure 5' 3' 3' 5'


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