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NEET UG 2026 » NEET UG Study Material » Chemistry » Salicylic acid
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Salicylic acid

Meta Description: Salicylic acid is a natural substance. It's a colourless, bitter-tasting substance that serves as a precursor and metabolite for aspirin (acetylsalicylic acid).

Table of Content
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A beta hydroxy acid is salicylic acid. It’s well-known for eliminating acne and keeping pores clear by exfoliating the skin so it looks healthy.

Salicylic acid can be found in over-the-counter (OTC) products. Prescription-strength formulations are also available.

Mild acne responds best to salicylic acid blackheads and whiteheads. It may also aid in the prevention of subsequent outbreaks on skin.

Mechanism of action

Salicylic acid reduces the synthesis of pro-inflammatory prostaglandins through modulating COX-1 enzymatic activity. Salicylate can act as a competitive inhibitor of prostaglandin synthesis. The antirheumatic nonsteroidal anti-inflammatory properties of salicylate are due to its analgesic and anti-inflammatory properties.

Salicylic acid works by causing epidermal cells to shed more easily, preventing pores from clogging and allowing room for new cell development. Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with nicotinamide adenine dinucleotide. It also prevents the glucuronyl group of uridine-5-diphosphoglucuronic acid from being transferred to the phenolic acceptor.

Salicylates’ wound-healing inhibitory action is most likely owing to their inhibitory action on mucopolysaccharide production.

Uses

This medication is used to treat acne that is mild or moderate. It’s possible to use it alongside other acne treatments. Before mixing acne treatments, consult your doctor or pharmacist. Salicylic acid is also a member of the salicylates drug class. Salicylic acid may help the skin shed dead cells from the top layer and reduce redness also swelling when applied to the skin (inflammation). This reduces the quantity of pimples that appear and speeds up the healing process of skin.

How to use salicylic acid topical

Follow the product’s instructions to the letter. Inquire with your doctor or your pharmacist if you have any concerns.

Check to see whether you are allergic to this product before using it for the first time. Apply a small amount to one or two minor areas of acne for three days to see whether it works to see if you develop an allergic reaction to this product then stop using it immediately and seek medical attention (see the symptoms of an allergic reaction in the Side Effects section). You can use the product only if you don’t have an allergic reaction to it.

This drug is to be used on the skin. Do not let this drug come into contact with your eyes, nose, mouth, groyne, or any broken skin to avoid irritation (such as cuts, scrapes, rashes). If you receive the medication in certain locations, rinse it out for 15 minutes with lukewarm water.

Apply a thin layer of the medication to the parts of your skin affected by acne, normally 1 to 2 times a day or as advised by your doctor, if you’re using a cream, lotion, solution, or gel. Wash the affected area lightly with a mild cleanser before applying each dose, then pat dry. A small amount of medication should be applied to the affected area and gently rubbed in. If you’re going to use the pads, wash the affected area with a mild cleanser before patting it dry. To apply the medication, gently wipe the pad over the skin 1 to 3 times a day or as instructed by your doctor. After each use, wash your hands.

If you’re going to use a cleanser with salicylic acid, make sure you moisten the affected area first. For 10 to 20 seconds,  massage the cleanser into the skin. Scrubbing the skin is not a good idea. Rinse well and pat dry after working up a thick lather. If the cleanser dries out too much, you may need to rinse it off sooner or use it less frequently. For more information, talk to your doctor or to your pharmacist.

Dosage is determined by your medical condition and what your treatment response is. Do not take larger doses or apply this medication more frequently or use it for longer than recommended. Your condition will not improve faster, but the risk of side effects will be higher.

If your ailment persists or worsens, or if you suspect you may have a significant medical concern, seek medical help right away.

Does salicylic acid have any side effects

Although salicylic acid is generally regarded as harmless, it might cause skin irritation when used for the first time. It may also eliminate too much oil which may leave your skin dry and irritated.

The following are some possible adverse effects:

  • skin tingling or stinging
  • itching
  • peeling skin
  • hives

Precautions to be aware of before using salicylic acid

Despite the fact that salicylic acid is available over-the-counter at your local shop, you should consult your doctor before using it. The following are some things to think about:

  • Allergies. If you’ve had previous allergic reactions to salicylic acid or other topical treatments, tell your doctor.
  • Children’s use. Because children’s skin absorbs salicylic acid at a much faster rate than adults’, they may be more susceptible to skin irritation. Children under the age of two should not be exposed to salicylic acid.
  • Interactions between drugs. Salicylic acid interacts poorly with a number of medicines. Tell your doctor about any medications you’re taking as of right now.

Conclusion

Salicylic acid is a medication that aids in the removal of the skin’s outer layer. Warts, skin tags, calluses, psoriasis, dandruff, acne, ringworm, and ichthyosis are all treated with it. It is frequently used in conjunction with other drugs for problems other than warts. It’s applied to the affected area.

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Frequently asked questions

Get answers to the most common queries related to the NEET UG Examination Preparation.

What is the effect of salicylic acid on the skin?

Topical salicylic acid reduces swelling and redness while also unclogging blocked skin pores, allowing pimples to di...Read full

Can I take salicylic acid on a daily basis?

Is it safe to take salicylic acid on a daily basis? While using salicylic acid on a daily basis is safe, it can caus...Read full

Is salicylic acid beneficial to the skin?

Salicylic acid is an acne-fighting chemical that can be found in skin care products. By breaking down and eliminatin...Read full

Is salicylic acid effective in the treatment of pimples?

Salicylic acid may help the skin shed dead cells from the top layer and reduce redness and swelling when applied to ...Read full

Is it OK to combine vitamin C and salicylic acid?

Glycolic, salicylic, and lactic acids are examples of AHAs and BHAs that should never be used with Vitamin C. Layeri...Read full

Topical salicylic acid reduces swelling and redness while also unclogging blocked skin pores, allowing pimples to diminish. It softens and loosens dry, scaly, or thickened skin so that it slips off or can be readily removed to treat other skin diseases.

Is it safe to take salicylic acid on a daily basis? While using salicylic acid on a daily basis is safe, it can cause irritation. As a result, many dermatologists advise using the acid in moderation, starting with three applications each week and gradually increasing.

Salicylic acid is an acne-fighting chemical that can be found in skin care products. By breaking down and eliminating dead skin cells and oil, salicylic acid can help unclog blocked pores. Skin irritation or peeling are possible side effects of salicylic acid.

Salicylic acid may help the skin shed dead cells from the top layer and reduce redness and swelling when applied to the skin (inflammation). This reduces the quantity of pimples that appear and speeds up the healing process.

Glycolic, salicylic, and lactic acids are examples of AHAs and BHAs that should never be used with Vitamin C. Layering these substances together will throw off the pH balance and may as well be useless because vitamin C is an acid and is unstable.

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