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NEET UG 2026 » NEET UG Study Material » Biology » Spindle Fibres
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Spindle Fibres

Spindle fibre is a network of filaments that helps to generate the mitotic and meiotic spindles during cell division. Spindle fibres are responsible for the movement of chromosomes during cell division during mitosis and meiosis.

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During cell division, spindle fibres are responsible for the formation of the mitotic and meiotic spindles. During nuclear division, they are generated by microtubules and play a key role in the process. When cells divide during mitotic and meiotic division, they are in charge of ensuring that sister chromatids are separated as well as the movement of chromosomes.

What Are Spindle Fibres and How Do They Work

Cellular structures that form during and participate in the cell division of eukaryotic cells include spindle fibres, which are microtubules that extend from centrosomes in a cell. Spindle fibres are also known as microtubules. In this way, spindle fibres play a crucial and vital role in the development and function of organisms and the cells that make them up. Spindle poles are centrosomes that are extended by microtubules and are located at the ends of microtubules. Spindle fibres are a word used to refer to the centrosomes and microtubules that extend from them in a cellular context. But, more specifically, what is the function of the spindle fibres? In order to understand why spindle fibres are vital, it is first necessary to understand cell division in general, why organisms require it, and the two specific types of cell division that occur in each cell.

Definition of spindle fibres

A structure consisting primarily of microtubules and centrosomes, as seen in this diagram.

Cell Division: The Process by Which Humans and Other Organisms Develop

During a cell’s life cycle, cell division involves the replication of its DNA and chromosomes, followed by the division of its nucleus and the division of its cytoplasm. Cell division is a crucial step in the development of a cell’s identity. It is the nucleus of a cell that contains the DNA that is packed into chromosomes in order to facilitate the replication of the cell. This fluid-filled space surrounds the nucleus and contains many organelles that are floating within it. The objective of cell division is the replication of a cell in its environment. Cells reproduce in order for the creatures they form to be able to grow, mature, and heal when the situation calls for them. Aside from that, cell division is an important aspect of the process of reproduction. Spindle fibres are involved in both meiosis and mitosis, which are two types of cell division. Meiosis is a cell division process that results in the formation of gametes or sex cells, whereas mitosis is a cell division process that results in the formation of duplicated body cells.

Meiosis is the process of cell division.

Gamete-producing cells, or cells that divide into sex cells such as sperm and eggs for the purpose of sexual reproduction, go through the process of meiosis, which is a type of cell division that occurs in the body. When a single gamete-producing cell divides twice, it produces four gametes, which is the result of the meiotic division process. Each of the gametes has a random half of the alleles or choices for each gene included in the parent cell, resulting in a total of four gametes per parent cell. As a result, each gamete is genetically distinct from the others, resulting in genetic variances among offspring that were sexually reproduced by the same parents but from different parents. It is important for the evolution of species that there be variation.

Prophase, metaphase, anaphase, and telophase are all stages of the cell division process that take place during meiosis. Before the division of the cytoplasm takes place, the cell goes through prophase, metaphase, anaphase, and telophase. Despite the fact that the cell goes through PMAT twice, each phase is slightly different. Both of these cell division procedures are critical because each produced gamete must have the necessary number of chromosomes in order to be a viable organism. During sexual reproduction and fertilisation, it is necessary for a gamete to be haploid, which is a cell that has half of its parent cell’s DNA, in order for it to join with another haploid gamete and produce a fertilised egg. Both gametes join to produce a zygote, also known as a fertilised egg, which is a diploid cell that includes the correct number of chromosomes and the entire complement of genes. In each cell of an organism, there are necessary life activities that take place, and these processes are all guided by the genetic information contained within the chromosomes of each cell. A gamete with an improper number of chromosomes can result in genetic and birth problems if both occurrences of PMAT are not performed successfully, and the gamete is not removed from the egg.

Mitosis is the process of cell division

Spindle fibres are also involved in the process of mitosis, which is another type of cell division. Mitosis, on the other hand, is not a cell division process that is specifically designed for gamete-producing cells and gametes. It is a process that occurs within a cell division that is experienced by all body cells of an organism for the purposes of growing the organism to maturity and repairing damage by replacing dead or damaged cells that make up the organism. Mitosis is a cell division that occurs in all body cells of an organism. When a body cell goes through mitosis, its nucleus is divided into two distinct nuclei, which is known as nuclear division (or nuclear division). These nuclei are subsequently separated into two separate cells during cytokinesis, which occurs when the cytoplasm of the parent cell completely divides, effectively completing the cell division. Each of the resultant body cells after mitosis is an identical diploid cell, and as a result, each of the resulting body cells includes a complete set of chromosomes that are identical to the chromosomes of the parent cell.

Conclusion 

Spindle fibres are generated during both the mitotic and meiotic divisions of the cell.

Spindle fibres bind to kinetochores and arms of chromosomes and aid in the segregation and migration of chromatids during cell division and division.

With the help of the spindle, the chromosomes are aligned in the centre and then travel to the opposite poles during anaphase stage, which occurs between metaphase and anaphase.

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Frequently asked questions

Get answers to the most common queries related to the NEET UG Examination Preparation.

What is a spindle fibre, and how does it work?

Ans. Cell division results in the formation of a network of filaments, which is known as a spindle fibre network. Wh...Read full

What is the composition of spindle fibres?

Ans. The microtubule, which is a polymer of and -tubulin dimers, is the component of spindle fibre that is found in ...Read full

What are the differences between the two types of spindle fibres?

Ans. The kinetochore and interpolar fibres are the two types of spindle fibres that can be found. The interpolar is ...Read full

What is it that adheres to the spindle fibres?

Ans. In metaphase, spindle fibres bind to the centromere of each sister chromatid, forming a ring around the cell (s...Read full

What causes the lengthening and shortening of spindle fibres?

Ans. Spindle fibres are the microtubules that make up the spindle, and they are made up of repeating tubulin subunit...Read full

Is it possible to see spindle fibres during metaphase?

Ans. Mitosis is divided into four stages that occur sequentially: prophase, metaphase, anaphase, and telophase. Ther...Read full

Ans. Cell division results in the formation of a network of filaments, which is known as a spindle fibre network. When chromosomes are moved during the processes of mitosis and meiosis, they are called chromosome transporters.

Ans. The microtubule, which is a polymer of and -tubulin dimers, is the component of spindle fibre that is found in the greatest abundance. Additionally, the spindle fibre is composed of several hundreds of proteins that are connected with it.

Ans. The kinetochore and interpolar fibres are the two types of spindle fibres that can be found. The interpolar is a continuous stretch that runs from one spindle to another. The kinetochore fibre connects the pole to the kinetochore and then back to the pole.

Ans. In metaphase, spindle fibres bind to the centromere of each sister chromatid, forming a ring around the cell (see Figure below). All of the sister chromatids are aligned at the equator, or centre, of the cell’s surface. This is referred to as the metaphase plate in some circles.

Ans. Spindle fibres are the microtubules that make up the spindle, and they are made up of repeating tubulin subunits that are placed end-to-end. Through the addition and removal of tubulin subunits, the fibres can be made longer or shorter as a result of the modular character of the protein.

Ans. Mitosis is divided into four stages that occur sequentially: prophase, metaphase, anaphase, and telophase. There is a condensed and more obvious appearance for each chromosome during prophase, as well as disruption of the nuclear membrane, as well as the emergence of spindle fibres. The chromosomes align themselves along the metaphase plate during the following phase, prophase.

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