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NEET UG 2026 » NEET UG Study Material » Biology » Microtubules
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Microtubules

In this article we are going to learn on the topic of MICROTUBULES in detail with examples..

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Microtubules are polar molecules that have a positively charged end that grows quickly and a negatively charged end that grows slowly. Microtubules are polar molecules that have a positively charged end that grows quickly and a negatively charged end that grows slowly. Microtubule protofilaments align themselves in a row parallel to one another, exposing beta subunits at the positive end and alpha subunits at the negative end, resulting in the formation of a microtubule.

Microtubules play an important role in many processes.

Microtubules are involved in the following processes in which they are important:

Cellular Activity is a term used to describe the activity of cells.

Microtubules are responsible for the formation of cilia and flagella. They also assist in the movement of cells by allowing the contraction and expansion of the cell to take place more easily.

Cell division is the process by which cells divide.

Microtubules are used in the construction of mitotic spindles. These spindles are responsible for the organisation and separation of the chromosomes during mitosis.

Cellular Transport is a term used to describe the movement of cells.

Microtubules are responsible for the movement of organelles in the cytoplasm of the cell. Moreover, they aid in the transmission of information between different parts of the cell.

Microtubules that are well-organized in the intracellular space

Microtubules organise themselves into a network in the cytoplasm. The cytoskeleton, which is found in microtubules, is involved in chromosome segregation, transport, mobility, and mechanical support. Microtubules are able to transport cellular components and other substances because of motor proteins. It has the ability to either shrink or grow in order to generate energy.

Depending on the cell type, microtubules are arranged in a specific manner. It would be easier to transport organelles, vesicles, and proteins if the cell’s apical-basal axis was more easily accessible. Cell migration is aided in part by the presence of these molecules.

What is the role of the microtubule in the body?

Microtubules are similar to actin filaments in that they are constantly assembling and disassembling within the cell, so it is important to remember this. Several cell movements, including cell locomotion, organelle transport within the cell, and the separation of chromosomes during mitosis, are controlled by these proteins, which are also responsible for the shape of the cell.

Microtubules Have a Specific Shape

They are responsible for arranging microtubules in the cytoskeletal network of cells. These structures are found in the eukaryotic cells. During the interphase, microtubule-organising centres (MOCs) constitute the vast majority of animal cells in the body. Dynamin and kinesin are two proteins that are known to interact with microtubules and are found in many different types of cells.

Tubulin is a subunit of the microtubule protein complex. Each tubulin molecule contains two tubulins: an alpha tubulin and a beta tubulin. Tubulin is found in this instance to be a heterodimer. Microtubules play an important role in the function of eukaryotic cells. They release tubulin protein in a normal manner, which involves transcription of the tubulin gene, which results in RNA, followed by transcription of mRNA, which results in the production of the proteins required for tubulin production. The term “lumen” refers to the lumen, or lumen interior, of a microtubule cylinder.

Actin Filaments Play a Critical Role in the Body

Actin is a protein found in high concentration in all eukaryotic cells. Actin is a protein that is arranged in filaments. Strict muscles, which are composed of striated muscle, were the first to be observed to exhibit this phenomenon. While in the presence of nonmuscle cells, actin filaments are less well-organized, and myosin appears to be significantly less prominent. Actin filaments are formed by the arrangement of identical actin proteins in a long spiral chain, which is formed by the arrangement of identical actin proteins. In the same way that microtubules have two ends, actin filaments have two ends, with the plus end of an actin filament producing the most ATP for growth.

Various cell types have actin filament networks beneath their cortexes, which can be observed in a variety of ways. Due to their ability to bind to membrane-associated proteins, actin filament networks provide support and strength to the cell wall. It is possible for such networks to transport and move highly specialised shapes, such as the comb border of microvilli. Actin filaments are also involved in the processes of cytokinesis and cell movement.

Microtubules that are well-organised in the intracellular space

Microtubules organise themselves into a network in the cytoplasm. The cytoskeleton in microtubules is responsible for a variety of functions including chromosome segregation, transport, mobility, and mechanical support. Because motor proteins allow cellular components and other objects to be transported along microtubules in order to obtain energy, it has the ability to either shrink or grow depending on the situation.

Microtubule arrangements are unique to a single cell type and cannot be replicated. It would be easier to transport organelles, vesicles, and proteins if the cell’s apical-basal axis was more easily accessible. Cell migration is aided in part by the presence of these molecules.

Conclusion:

Microtubules are responsible for the mechanical support of intracellular transport in the cell.

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Frequently asked questions

Get answers to the most common queries related to the NEET UG Examination Preparation.

What are microtubules and how do they work?

Ans : During the formation of a cell’s cytoskeleton, a network of protein filaments known as ...Read full

Microtubules are found in human sperm for a variety of reasons.

Ans : Flagella are found in some bacteria, and flagella are also found in human sperm, where they m...Read full

What is the nature of the interactions between microtubules during prophase?

Ans : It’s possible that the spindle microtubules’ side-to-side interactions are also a...Read full

What is the function of flagella and microtubules in the movement of a cell?

Ans : Flagella, which resemble tail-like appendages, are the means by which cells propel themselves...Read full

examples of microtubule fibres that are involved in cell division?

Ans : These two types of microtubule fibres, known as polar fibres and kinetochore fibres, are impo...Read full

Ans : During the formation of a cell’s cytoskeleton, a network of protein filaments known as microtubules, which are microscopic hollow tubes made of the proteins alpha and beta tubulin, are woven together. Microtubules are responsible for the shape of a cell as well as the stability of its organelles. The cytoskeleton is composed primarily of microtubules, which are 24 nanometers in diameter and 24 nanometers thick.

Ans : Flagella are found in some bacteria, and flagella are also found in human sperm, where they move. By contracting at one end of the microtubule and expanding at the other, microtubules also allow cells to crawl or migrate. Microtubules play a significant role in the formation of the mitotic spindle, also known as the spindle apparatus.

 

Ans : It’s possible that the spindle microtubules’ side-to-side interactions are also at play. When a cell enters prophase, the mitotic spindle takes over the function of the cytoplasmic microtubules.

Ans : Flagella, which resemble tail-like appendages, are the means by which cells propel themselves forwards. Flagella are found in some bacteria, and flagella are also found in human sperm, where they move. Additionally, microtubules enable whole-cell “crawling” or migration by contracting one end of a cell and expanding the other, allowing the cell to move from one location to another by contracting one end of a cell and expanding the other.

Ans : These two types of microtubule fibres, known as polar fibres and kinetochore fibres, are important in cell division. Besides centrioles and asters, which are both derived from microtubules, centrioles and asters are found in a wide variety of cell types. Animal cells have both of these structures, whereas plant cells do not have either of these structures. Centrioles are made up of microtubule clusters that are arranged in a 9 + 3 pattern.

 

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