Non-Cirrhotic Portal Fibrosis (NCPF)
NCPF (noncirrhotic portal fibrosis) is a syndrome with an unknown cause that is characterised by obliterative portal venopathy, portal hypertension, severe splenomegaly, and well tolerated bouts of variceal bleeding in young adults with near normal hepatic function. NCPF is characterised by vascular lesions that can be found in the portal vein, its branches, or the presinusoidal portion of the liver. Idiopathic portal hypertension, hepatoportal sclerosis, obliterative portal venopathy of the liver, and non-cirrhotic intrahepatic portal hypertension are some of the alternative names for NCPF.
Clinical features
Patients are typically young and healthy, with one or more episodes of gastrointestinal bleed that have been well tolerated. The other major symptom is a lump in the left upper quadrant of the abdomen, which is caused by an enlarged spleen. Perisplenitis and splenic infection are typical causes of left upper quadrant pain, but NCPF can also manifest with glomerulonephritis or hypoxia.
Noncirrhotic portal hypertension (NCPH) refers to a group of vascular diseases that cause portal hypertension (PHT) in people who have normal synthetic liver function and a normal or mild hepatic venous pressure gradient, NCPH are characterised by the site of blood flow resistance.
Extrahepatic portal vein obstruction (EHPVO), noncirrhotic portal fibrosis (NCPF; or idiopathic PHT [IPH]), and schistosomiasis are the most common causes of NCPH. Unlike many disorders like primary biliary cirrhosis or hepatic venous outflow blockage, where PHT is subsequent, IPH or NCPF is a major cause of NCPH. NCPF (as it is known in India), IPH (as it is known in Japan and Southeast Asia), and hepatoportal sclerosis (as it is known in Western nations) are all similar diseases.
National Curricular and Pedagogical Framework (NCPF)
Early childhood development is aided by the curriculum, which provides possibilities for comprehensive learning and growth. The ECCE curriculum should be centered on the developmental and contextual needs of the children, with more need-based inputs and a supportive atmosphere. Given the necessity for a tailored approach, it was thought that a single “curriculum” would not be suitable for all. However, it has been recognised throughout time that the practical realities differ, and the majority of ECCE programmes currently available do not contain developmentally appropriate programmes for the young child.
This Framework is a living document that will be evaluated and updated in response to changing demands. Case studies of emerging best practices will also follow the framework’s adoption, and learning from them will enrich the framework even more. Each programme is expected to create its own curriculum to fulfill the needs of its students, their families, the specific setting, the language culture, and the surrounding community. The programmes should, however, follow the curriculum ideas and norms outlined in this framework.
Aim of NCPF
This Framework is strongly focused on the needs of the child and should result in enhanced child care and a developmentally appropriate setting for children, resulting in improved learning quality and increased learning outcomes for children enrolled in ECCE programmes. In addition, this framework focuses on establishing guidelines for child care and early education methods. The other components of the comprehensive ECCE programme, including nutrition, health and hygiene, protection, and care, will be ensured by cross-referencing associated policies and instruments as outlined in the National ECCE policy.
Program of NCPF
This Framework is strongly focused on the needs of the child and should result in enhanced child care and a developmentally appropriate setting for children, resulting in improved learning quality and increased learning outcomes for children enrolled in ECCE programmes. In addition, this framework focuses on establishing guidelines for child care and early education methods. The other components of the holistic ECCE programme, such as nutrition, health and hygiene, protection and care, are to be ensured by cross-referencing from parents as caregivers are critical in providing a stimulating learning environment for the child, and the child does not need to be in a formal learning environment for the first two and a half to three years.
By offering principles for child care and early educational activities, this framework aims to enhance quality and excellence in early childhood care and education. The framework is meant to serve as a guide for ECCE service providers in all regions. It wants to help early childhood educators, service providers, ECCE teachers/caregivers, communities, and state governments deliver rich early stimulation and learning experiences for children from birth through pre-primary school. Families with small children may also find this document useful.
Conclusion
NCPH is a name used to describe a wide range of vascular disorders of the liver, including NCPF (in the East), IPH (in the West), and EHPVO. The clinical syndromes are unique and easy to diagnose, despite the fact that the etiopathogenesis may differ. The evaluation and treatment of a procoagulant condition is beneficial. The use of endoscopy in the treatment of acute variceal bleeds and the prevention of rebleeding improves patient survival. Interventional radiology and surgical therapy are both effective rescue treatments.
Framework NCPF is a living document that will be evaluated and updated in response to changing demands. Case studies of emerging best practices will also follow the framework’s adoption, and learning from them will enrich the framework even more. Each programme is expected to create its own curriculum to fulfill the needs of its students, their families, the specific setting, the language culture, and the surrounding community.