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NEET UG 2026 » NEET UG Difference Between » Gene and DNA
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Gene and DNA

Gene and DNA are vital components in the field of genetics. Many times these terms are interchangeably used. In general, a gene is a tiny part of DNA.

Table of Content
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DNA exists in a stable structure called double-helix, is organized into chromosomes, and is the genetic blueprint of almost every organism. On the other hand, genes are a small part of the DNA and are the hereditary molecules transferring traits to the progeny. Genes are basically composed of both DNA and RNA. When it comes to the main difference between genes and DNA, on the one hand, DNA is a chemical structure storing the genetic instructions for an organism. On the other hand, genes are small DNA stretches determining the particular trait of an organism. 

What is a Gene?

A gene is a region of a sequence of specific nucleotides on the DNA or RNA strands. The gene encodes an amino acid sequence of a particular protein. One can discover thousands of genes within a single DNA in higher organisms. Now that the genetic instructions transfer into the progeny via reproduction through the genes, the same is recognized as the molecular unit of heredity. The sequence of a gene is transcribed into mRNA, which is transcribed into proteins determining the trait of an organism. This entire process is referred to as the central dogma of molecular biology.

It is discovered that almost every gene found in the body of an organism is made up of DNA, but some genes may share RNA. 

It is based on the legacy of the phenotypic trait of an organism that the transmission of genes is done. These genes contribute a lot to developing the different sequences of DNA. This sequence is also referred to as genotype. 

It is on the environmental and developmental factors based on which it is determined by the genotypes that which phenotypes will take place. Most of the biological characteristics are under the control of polygenes and interactions between genes and the environment. The polygenes are nothing but the collection of many different genes. 

What is DNA?

Deoxyribonucleic acid, popularly known as DNA, is the genetic material of almost every organism. It is a molecule consisting of a double helix that further carries the genetic instructions necessary for the functions, growth, development, and reproduction of organisms and viruses. 

DNA is composed of two polynucleotides and is located in the nucleus and nucleoid. Each nucleotide is composed of one of the four nitrogen-containing nucleobases that include cytosine, thymine, guanine, or adenine. This particular collection also includes a sugar referred to as deoxyribose and a phosphate group. 

It is the chain by covalent bonds in which the nucleotides are linked to each other. And this particular bond is called phosphodiester linkage. The link is between the phosphate of one nucleotide and sugar of the other nucleotide, resulting in an alternating sugar-phosphate backbone. 

The nitrogenous bases of two different polynucleotide strands and the hydrogen bonds are bound together to form a double-stranded Deoxyribonucleic Acid (DNA). Pyrimidines and purines are the two groups into which the complementary nitrogenous bases are further separated. In DNA, the pyrimidines include thymine and cytosine, while adenine and guanine are present in the purines.

Both strands of double-stranded DNA act as the storage unit storing similar biological information. It is during the separation of the two strands, that the biological information is reproduced. DNA consists of approximately more than 98 percent of humans. 

Gene and DNA: Difference

Here mentioned is the difference between gene and DNA in the tabular form:

Gene

DNA

Genes are referred to as the DNA stretches determining the specific trait of an organism

DNA is referred to as a biomolecule that consists of the genetic information of an organism

Gene is basically a particular sequence that is present on a small stretch of DNA

DNA is composed of two long chains of polynucleotides wound together

Gene performs the function of regulating the traits of an organism

DNA performs the function of regulating the gene regulation in an organism

It consists of either DNA or RNA

DNA is basically a polymer of nucleotides

Gene is coded with the hereditary instructions of an organism

The genetic instructions of an organism are encoded by DNA

When it comes to the location, the gene is present on the chromosome

When it comes to the location of DNA, it is present within the nucleus of the cell

Conclusion

DNA, on one hand, is the building block of genes containing the genetic instructions for an organism. On the other hand, Genes are a small part of DNA, the main function of which is making particular proteins that further contribute a lot to the structure and functions of the body. To know more about the difference between these two, go through the article.

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What is meant by genome?

Answer: Genomes are nothing but a complete set of genetic instructions determining the traits of almost every...Read full

What is a chromosome?

Answer: Genes are packaged into bundles referred to as chromosomes. It has been researched that a huma...Read full

What is meant by genetic variation?

Answer: Genes in the organism are prone to coding errors leading to genetic variation. Some errors do not hav...Read full

Answer: Genomes are nothing but a complete set of genetic instructions determining the traits of almost every organism. It is composed of genes, chromosomes, and DNA. Genomes determine how an organism will grow, look, age, and how the body will develop during pregnancy. Not only this, but the genome determines how cells, tissues, and organs of the body will function.

 

Answer: Genes are packaged into bundles referred to as chromosomes. It has been researched that a human body consists of 23 pairs of chromosomes, making a total of 46 individual chromosomes. These are present in the nucleus of almost every cell of the human body. The pair of chromosomes, called X and Y chromosomes, determine whether an individual will be born male or female.

Answer: Genes in the organism are prone to coding errors leading to genetic variation. Some errors do not have a major impact on the structure or functions of an individual’s body, but others can have. There are three types of genetic variations- genetic mutations, genetic recombination, and genetic migration.

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