CERAMIDES AND SPHINGOMYELIN

Introduction 

There are various factors regarding the formation, components and the various applications of ceramide and sphingomyelin. In that case, it can be said that there are various types of formation and components that can be used for forming ceramide and sphingomyelin. In that case, it can be said that there are various types of applications and benefits of these components which will be discussed in this assignment. The factors of these biomolecules will be discussed and elaborately described in this assignment with the help of various evidence and the accurate application of the components. Thus, the assignment is going to focus on these factors with the various discussions and resources regarding these components of the human body and eukaryotic cells.  

Central Discussion 

Chemical Structure of Ceramide

Ceramide is the chemical compound that belongs to the waxy lipid family and this is the compound molecule formed of more than one simple molecule. This compound is a combination or made of Sphingosine and Fatty acid, which are found in Eukaryotic cells in high concentrations. On the other hand, it can be said that ceramide is the long chain of carbon atoms with the attachment of Amino Acid in it (Dermcollective.com, 2019). Apart from the natural source of ceramide, there are also some grains and food particles that can help to produce ceramides in a higher amount. There are some food components like milk, wheat, soy, eggs that have a large amount of Sphingolipid that can help to boost the power of producing ceramide.   

Types of Ceramide

There are various types of ceramide found in different spaces. In that case, it can be said that the major types of ceramide are Natural ceramide and Pseudo Ceramides (hrcak.srce.hr, 2019). Natural ceramides are the types of ceramides that are usually found in the outer layer of skin in animals like cows and in the various trees like soy etc. On the other hand, the pseudo ceramide are those which are human-made and those are also called Synthetic Ceramides. In that case, it can be said that there is some difference in the fatty acid bond in the different types of ceramide, the different forms of fatty acid bonds help to create the various types of ceramide (Skinkraft.com, 2020). Usually, there are 12 types of ceramide which are named Ceramide 1 to 12. In that case, there are some common types of ceramide that are used popularly in the various types of skincare and personal care products. 

• Ceramide 1 [Ceramide EOS]

• Ceramide 2 [Ceramide NS or NG]

• Ceramide 3 [Ceramide NP]

• Ceramide 6-II [Ceramide AP]

• Ceramide 9 [Ceramide EOP]

Benefits and Uses of Ceramides

Ceramide is mainly used in skincare products for its specific features of restoring the moisture in the skin and it can also help in reducing skin irritation and various damage. Therefore, the main use of ceramide is the major component in skincare products (www.biomedcentral.com, 2019). In that case, it can be said that ceramide has a huge role in the treatment of Eczema and Psoriasis. On the other hand, this component can help to moisture and strengthen the outer and protective layer of the skin. 

Chemical Formation of Sphingomyelin 

The Sphingomyelin is a type of Sphingolipid, which is usually found in animal cell membranes and is also found in the membranous myelin sheath. On the other hand, it can be said that it is the specific type of Sphingolipid, which is surrounded by the thick layer of the myelin sheath. This component consists of Sphingosine (type of hydrodynamic), which is bonded with one fatty acid at the NH2 function in the one polar head group. This compound has a structure similar to the structural bond of phosphocholine or phosphoethanolamine with the CH2OH function. This is the plasma membrane component, which has a major role regarding the signaling in the neural pathways.       

Types of Various Sphingomyelin

There are various types of sphingomyelin based on the different types of use and the application and structural differences of the lipid bonds (www.sciencedirect.com, 2019). Those, various types of sphingomyelin can be mentioned as below:

• • Phosphatidylcholine
  • Phospholipid
  • Sphingolipid
  • Sphingosine
  • Glycosphingolipid
  • Ceramide

• Bilayer Membrane

• Cell Membrane    

Various Application of Sphingomyelin

Sphingomyelin consists of phosphocholine type of Sphingosine and fatty acid; therefore, it has a huge role in the pathways of signaling. On the other hand, this has a major role in the treatment of “cancer initiation, progression and immune evasion” (www.ncbi.nlm.nih.gov, 2020). The sphingomyelin has various roles in maintaining structural integrity and the absorption of some vital nutrients. On the other hand, it also provides various protections and acts as the receptor of the toxins and microbial antigens.

Conclusion

As per all the above discussion, the factors and the structural variations of the ceramide and sphingomyelin have been elaborately described here through the various data and information. In that case, the various implications of these components and the applications and benefits are also clearly described and concluded here. Overall, it can be said that the application and significance of ceramide and sphingomyelin have been described here along with the various factors related to those components.