Dr Praveen Kumar Agrawal is teaching live on Unacademy Plus
Course: Locomotion and Movement -2 Lesson -7:Structure and Chemistry of Myosin filaments DR. P. K. AGRAWAL M.Sc, PH.D., CSIR NET (JRF), SRF, GATE, FIAZ 20 Years of Pre-medical teaching experience Ex Faculty, Allen Career Institute, Kota Watch my Live Classes on Unacademy Plus
STRUCTURE OF A MYOSIN FILAMENT Myosin filaments are thick and dark coloured filaments. .A myosin filament is a thick filament. It is composed of multiple myosin molecules, about 200 in number. Each has a molecular weight of about 4,80,o00. The myosin molecule is comprised of six polypeptide chains 2 heavy (each with Mol. Wt. 2,00,000) and 4 light chain (each with Mol. Wt. 20,000). . The two heavy chains are coiled around each other, forming double helix. . One end of each of these chains is projected outwardly and it is known as cross bridge. This end is folded into a globular protein mass, called myosin head. Each head consists of two lobes. Two light chains are also associated with each lobe Myosin head has an special ATPase activity i.e., it can cleave ATP to produce energy. . Each lobe of the head contain two regions - ATP binding site and Actin binding site. . There are many myosin molecules in a filament. So, man heads remain projected out from the surface of the filament.
Structure of mysin filament and chemistry of myosin molecule Myosin Heads myosin filament Myosin molecules Hinge Myosfn Head Single myosin Molecule Shatt
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