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Introduction and Overview of the course
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Introduction to cell biology, cell theory and course overview

Malini Sundar Rajan
AIR20(GATE Biotech, 2017) DBT-JRF(Category-I fellowship, 2016) AIR19 (GATE Biotech, 2012) AIR10 (CSIR-NET Life Sciences, 2011)

Unacademy user
Sudheesh Raghavan
6 months ago
👍👍
Hi Mam,I also qualified with GATE BT in 2012(AIR 131) and in 2011(AIR 519).I graduated with MTech Clinical Engineering from IIT Madras in 2015.I am interested i Bioinformatics.I want to take up BINC exam.How to go about preparing for the same?
Malini Sundar Rajan
10 months ago
Thank you for your message. This is the first time I am hearing of BINC exam. I understand that there are three parts to this and that the third is practicals including programming. If you have no programming experience, I suggest that you start learning programming basics from unacademy as well as the grasshopper app by google. also pick up a simple language like C or Perl or python. I will get back to you if I find more nuanced information about this exam. Thank you.
Mohamed Rameez
10 months ago
Thank you mam
No problem. Don't hesitate to reach out to me on unacademy by private message if you have further questions :)
  1. Cell Biology By Malini Sundar Rajan B.E. Biotechnology M.Tech. Biotechnology GATE(BT) 2017 AIR 20 DBT BET 2016 qualified category l GATE (BT) 2012 AIR 19 CSIR UGC NET 2011-AIR 10 (CSIR-JRF) Student, Aptech Computer Education Unacademy profile: https://unacademy.com/user/maliniarsBT 1-Introduction and Course Overview All illustrations used in this lesson are in public domain


  2. Target Audience Aspirants of competitive exams in biology and life sciences GATE (BT) DBT-BET CSIR-UGC-NET (life sciences) ICMR (life sciences) JNU entrance exams (M.Sc and M.Tech Biotechnology programs) Other private college entrance exams for masters degree programs


  3. Cell Biology Syllabus (GATE BT) Q.5 The cytokinetic organelle in plant cells is Section 2: General Biotechnology (A) centriole (B) phragmoplast (C) proplastid (D) chromoplastid action potential and transport processes; Enzymes- classification, kinetics and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids) photosynthesis, respiration and electron transport chain: Bioenergetics .31 Microbiology: Vinuses structure and classification; Microbial classification anc diversity[bacterial, algal and fungol: Methods in microbiology: Microbial growth anc nutrition; Aerobic and anoerobic respiration; Nitrogen fxation; Microbial diseases anc host-pathogen interaction Match the drugs in Group I with their mechanism of action in Group II GroupI P) Paclitaxel R) Etoposide I) Inhibits protein translation 2) Inhibits microtubule depolymerization 3) Inhibits DNA replication 4) Alkylates DNA 5) Inhibits dihydrofolate reductase 6) Inhibits microtubule polymerization Cell Biology: Prokaryotic and eukaryotic cell structure: Cell cycle and cell growth control Cell-Cell communication, Cell signoling and signal transduction S) Methotrexate Molecular Biology and Genetics: Molecular structure of genes and chromosomes Mutations and mutagenesis; Nucleic acid replication, transcription, translation and thei regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance: Gene interaction: chromosomal inheritance: Microbial genetics (plasmids, transformation, transduction conjugation]: Horizontal gene transfer and Transposable elements: RNA interference: DNA damage and repair; Chromosomal variation: Molecular basis of genetic diseoses Analytical Techniques: Principles of microscopy-light, electron, fluorescent and confocal; Centritugation- high speed and ultra: Principles of spectroscopy-UV, visible. CD, IR. FR (A) P-1, Q-6, R-3, S-4 (C) P-1 Q-3, R-6, S-5 (B) P-2, Q-6, R-3, s-5 (D) P-2.Q-3, R-6, S-4 Linkage, recombination and chromosome mapping: Extrc Question Number: 18 Correct: 1 Wrong:-0.33 on exchange, gel filtration, hydrophobic interaction, affinity, GC,HPLC. FPLC: Electrophoresis; Microaray Immunology: Hstory of Immunology: Innate, humoral and cell mediated immunity Antigen; Antibody structure and function: Molecular basis of anfibody diversity: Synthesis of antibody and secretion: Antigen-antibody reaction Complement: Primary and secondory lymphoid orgon: B and T cells and macrophoges: Major complex (MHC): Antigen processing and presentation: Polyclonal and monocional antibody; Regulation ofimmune response: Immune tolerance: Hypersensitivity Autoimmunity: Graft versus host reaction, In eukaryotes, cytokinesis is inhibited by (A) cytochalasin D (B vinblastine Question Number:41 (C) nocodazole (D) colchicine Correct: 2 Wrong: 0.66 The genome is diploid at the end of which phases of a human mitotic cell cycle? (A) G2 &S (B) Gl & M (C) M&S (D) Gl & G2


  4. What is Cell Biology? The study of cells What are cells? the smallest structural and functional unit of an organisnm which is typically microscopic and consists of cytoplasm and a nucleus enclosed in a membrane basic structural, functional, and biological unit of all known living organisms "Building blocks of life" Smallest unit of life General view of cells in the growing root-tip of the onion, from a longitudinal section, enlarged 800 diameters a. non-dividing cells, with chromatin-network and deeply stained nucleoli; b. nuclei preparing for division (spireme-stage); c. dividing cells showing mitotic figures; e. pair of daughter-cells shortly after division Ilustration by E.B. Wilson, 1900, The Cell in Development and Inheritance


  5. Cell Theory Robert Hooke (1635-1707) first observed cells (cork specimen) Anton van Leeuwenhoek (observed living cells) Theodor Schwann, Matthias Schleiden, and Rudolph Virchow (proposed cell theory) - All lving organisms are composed of cells. They may be unicellular or multicellular The cell is the basic unit of life - Cells arise from pre-existing cells (They are not derived from spontaneous generation) - Robert Hooke's Robert Hooke's microscope illustration of suber cells and mimosa leaves


  6. Syllabus Overview Cell Biology: Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-Cell communication, Cell signaling and signal transduction . Prokaryotic Cell and Eukaryotic cell structure . Cell cycle and cell growth control . Cell-to-cell communication, cell signaling and signal transduction


  7. Course Plan .Size of cells and microscopy Prokaryotic cell and eukaryotic cell structure Plant cell and animal cell Plasma membrane Fluid mosaic model Cell Cycle and Mitosis Meiosis Cytoskeleton . Cell-to-cell communication Cell Signaling and signal transduction


  8. Questions? Suggestions? Feedback? .Leave a comment! Or message me on unacademy Liked the course? Rate the course Leave a review Upvote the lesson Share with friends Malini Sundar Rajan Unacademy profile: https://unacademy.com/user/malinigrsBT Unacadem pofi htps/acaey.comu/malinarsaT