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DNA Replication,Part-6(in Hindi)
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This lesson talks about unwinding of DNA.

Umesh Kushawaha
Educator in Pre Medical Category Over 2200 MCQs in my feed

U
Unacademy user
How you have assigned the weighted values (.4, .3 ,.2....) for the different demand values?
Deepali Namdeo
a year ago
This is what the method says. 40% weightage is given to the most recent demand and so on. These weightage values are fixed. 40%,30%,20% and 10%
thanks again sir.. apka diya hua har concept clear ho jata h hume kuch aur read krne ki need nhi hoti bas revision krna h Q's solve ho jata h plz upload more n more
Umesh Kushawaha
a year ago
thank you....wait for next . main thoda slow hu ....filhal me. but January se everything will be very normal.
Neelima Maurya
a year ago
no sir slow bt regular ho ap..thank u so much hm sab ke liye itna kuch krne k liye
Umesh Kushawaha
a year ago
thank u neelima
  1. UMESH KUSHAWAHA


  2. Mechanism of DNA replication By umesh kushawaha


  3. 2 main steps - 1. Unzipping (unwinding) 2. Formation of new chain


  4. 1. UNZIPPING (UNWINDING) SEPARATION OF BOTH STRANDS OF DNA FROM EACH OTHER, IS CALLED UNZIPPING IT CAN NOT BE DONE WITHOUT BREAKING H2 BONDS.


  5. ORIGIN OF REPLICATION OR INITIATION POINT THE POINT AT WHICH THE PROCESS OF UNZIPPING STARTS IS CALLED ORIGIN OF REPLICATION OR INITIATION POINT


  6. WHAT ABOUT PROKARYTOES? THERE ARE ONLY ONE ORIGIN OF REPLICATION IN DNA MOLECULE THUS UNZIPPING STARTS AT SINGLE POINT.


  7. WHAT ABOUT EUKARYOTES? MANY ORIGIN OF REPLICATION. THUS UNWINDING STARTS AT MANY POINTS


  8. NICKING A PROCESS OF DOING A CUT IN ONE STRAND OF DNA WITH THE HELP OF TOPOISOMERASE ENZYME (A TYPE OF ENDONUCLEASE)


  9. HELICASE SWIVELASE IT BREAKS THE H2 BOND IN UNZIPPING PROCESS Mg ACT AS COFACTOR HERE


  10. ALKALINE MEDIUM UNZIPPING IS ALWAYS DONE IN ALKALINE MEDIUM