Pursuing my Masters in Microbiology. Fun-loving and a chill person. Enthusiastic learner and teacher. Singer and pianist.

Akepogu Jacquelyn

Introduction to treponema, morphology, cultivation, resistance, antigenic structure and pathogenicity of Treponema pallidum. Venereal, late tertiary and congenital syphilis, laboratory diagnosis, epidemiology, immunity, prophylaxis and treatment.

English

Syphilis - GATE

Includes the list of topics that are going to be covered in this course.

Course Overview

General morphology of Spirochetes, presence of endoflagella which help in motility and two families that belong to Spirochetes. Presence of pathogenic and non pathogenic treponemes in humans and the different kinds of diseases caused by pathogenic treponemes.

Introduction to Spirochetes and Treponema

A detailed description of the morphology and cultivation of the organism.

Treponema Pallidum - Introduction, Morphology and Cultivation

Resistance exhibited by the organism, antigenic structure - reagin antibody, group antigen, polysaccharide antigen; pathogenicity seen in humans, monkeys and chimpanzees.

Resistance, Antigenic Structure and Pathogenicity.

A detailed study on primary lesion, secondary syphilis, latent infection and tertiary syphilis.

Venereal Syphilis

Late tertiary syphilis, congenital syphilis and laboratory diagnosis - specimen and microscopy have been discussed in detail.

Late tertiary syphilis, congenital syphilis and laboratory diagnosis

Reagin antibody year, antibody titre interpretation, biological false positive tests and group specific treponemal tests are discussed in detail.

Laboratory Diagnosis - Serological Tests

Treponema pallidum immobilisation fest, fluorescent treponemal antibody test, hemagglutination assay and enzyme immunoassays are discussed in detail.

Laboratory Diagnosis- Serological Tests -2

Diagnostic utility of serological assays, response to treatment and diagnosis of the disease are discussed in detail.

Diagnosis And Response To Treatment

Epidemiology, Immunity - cell mediated immunity, prophylaxis - prevention and treatment of the disease are discussed in detail with the preferred drugs of choice.

Lessons

10 lessons • 1h 37m

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Course Overview

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Introduction to Spirochetes and Treponema

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Treponema Pallidum - Introduction, Morphology and Cultivation

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Resistance, Antigenic Structure and Pathogenicity.

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Venereal Syphilis

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Late tertiary syphilis, congenital syphilis and laboratory diagnosis

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Laboratory Diagnosis - Serological Tests

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Laboratory Diagnosis- Serological Tests -2

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Diagnosis And Response To Treatment

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Epidemiology, Prophylaxis and Treatment