Pursuing my Masters in Microbiology. Fun-loving and a chill person. Enthusiastic learner and teacher. Singer and pianist.

Akepogu Jacquelyn

Introduction to antibodies, antibody structure - enzyme digestion, immunoglobulin chains, domains and immunoglobulin classes - IgG, IgA, IgM, IgD and IgE.

English

Antibodies - Immunoglobulins for GATE

Includes the list of topics that are going to be covered in this course.

Course Overview.

The definitions of antibodies and immunoglobulin molecules and the difference between them.

Introduction to Antibodies.

Enzyme digestion, immunoglobulin chains - light and heavy, variable and constant regions.

Antibody Structure.

Domain regions of immunoglobulins, hypervariable and framework regions, constant regions and hinge regions.

Immunoglobulin Domains.

The characteristic features of IgG type of immunoglobulin molecules, concentration in the serum, half life, function and mechanism of action against antigens.

Immunoglobulin Classes - IgG

Includes the characteristic features of IgA immunoglobulin molecules, serum concentration, normal levels, half life, function and mechanism of action against antigens.

Immunoglobulin Class - IgA

Highlights the characteristic features of IgM type of antibodies, serum concentration, normal level, mercaptoethanol digestion, function and mechanism of action.

Immunoglobulin Class - IgM

Important points of IgD and IgE type of antibodies are listed in this lesson. It covers the serum concentration, function and mechanism of action against antigens.

Immunoglobulin Classes - IgD and IgE

Multiple myeloma, heavy chain disease and cryoglobulinemia.

Abnormal immunoglobulins.

The concept of isotype, allotype and idiotype are discussed in detail.

Immunoglobulin specificities.

The concept of antibody diversity, class switching and its clinical significance.

Lessons

11 lessons • 1h 33m

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Course Overview.

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Introduction to Antibodies.

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Antibody Structure.

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Immunoglobulin Domains.

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Immunoglobulin Classes - IgG

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Immunoglobulin Class - IgA

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Immunoglobulin Class - IgM

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Immunoglobulin Classes - IgD and IgE

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Abnormal immunoglobulins.

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Immunoglobulin specificities.

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