Msc biochemistry., gold medalist, University Ranker (twice) , science blogger , like dancing,writing and travel to explore!

K Raksha 

DNA replication-transcription-translation-recombination-repair and control of gene expressions -csir ugc net preparation

Crack CSIR NET by studying MATHEMATICS, PHYSICS, LIFE SCIENCE, CHEMISTRY, EARTH SCIENCE on one online platform. Everything you need to crack JRF.

CSIR-UGC NET

English

Fundamental Processes: CSIR UGC NET

Foundations of Biochemistry

Fundamental Processes

Life Sciences

NET Exams

Ace the toughest competitive and government exams in India 

Test Preparation

Strategic study plan, marks distribution and exam pattern is discussed in this session

An Overview of CSIR NET

An overview on DNA replication-transcription-translation-recombination-repair- gene regulation is discussed in this session

An Overview Lesson on Fundamental Processes

Replication Introduction and rolling circle model , theta model is explained in detail

DNA Replication Part 1

Initiation process with enzymes (in prokaryotes) is explained in detail 
Book reference: principles of biochemistry by leninger

Prokaryotic DNA Replication - Initiation

Elongation process of DNA replication  explained in detail

Prokaryotic Replication - Elongation

Termination process with proteins is explained in detail

Prokaryotic DNA replication - Termination

Initiation phase in eukaryotes - formation of pre - initiation complex is explained in detail

Eukaryotic DNA Replication - initiation

Elongation process of eukaryotic DNA Replication is discussed in this session . List of enzymes is also provided at the end

Eukaryotic DNA Replication- Elongation

Termination process in eukaryotes with end replication problem is discussed in this session

Eukaryotic DNA Replication- termination

Replication during cell cycle, differences between prokaryotic and Eukaryotic replication is discussed

Prokaryotic vs Eukaryotic DNA REPLICATION

An introduction to DNA Damage, it's source of damage and types are discussed in detail in this session

DNA damage

Introduction to DNA repair. Direct reversal repair and base excision repair system (BER) is discussed in detail

DNA repair Introduction

NER (nucleotide excision repair) and transcription coupled -NER is discussed in detail

DNA Repair system- NER ( nucleotide excision repair system)

Mismatch repair system with the Enzymes involving is discussed in detail

Mismatch repair system

Operon concept of SOS system ,sos proteins and error prone replication is discussed in this session

DNA repair -SOS Repair system

Homologous recombination by Robin Holliday - introduction  , proteins involved, resolution of Holliday structure is discussed in detail

Homologous recombination

Short summary of Homologous recombination with double break repair model and site specific recombination is discussed in detail

DNA recombination part 2

An overview of transcription process in prokaryotes and eukaryotes is discussed in this session

DNA Transcription -An introduction

Initiation phase of transcription process in prokaryotes is discussed in detail

Transcription in prokaryotes- Initiation

Elongation of RNA synthesis in prokaryotes is discussed with the RNA POLYMERASE and protein bridge factors

Transcription in prokaryotes- Elongation

Termination of transcription in prokaryotes is explained. Also brief summary of transcription process (all 3 stages) is discussed in this session

Transcription in prokaryotes- Termination

Introduction on transcription process in eukaryotes

Eukaryotic Transcription

This session begins with the figuring out differences between the 3 RNA polymerases continued by initiation process mediated by RNA Pol1 and Pol3

Eukaryotic transcription- Initiation

RNA POLYMERASE II mediated transcription is discussed in detail

Eukaryotic DNA Transcription

Elongation and termination process in Eukaryotic DNA Transcription along with elongation and termination factors is discussed in this session

Eukaryotic transcription- Elongation and termination

5' capping mechanism is explained in detail

Post-transciptional modifications- 5'capping

Polyadenylation mechanism is discussed in this session

Post-transciptional modifications-3'polyadenylatiom

This session begins with the introduction on RNA Editing continued with an apolipoprotein B as an example of modification

Post-transciptional modifications- RNA Editing

Addition and deletion mechanism by gRNA is discussed in this session

Post-transciptional modifications- RNA Editing 2

Introduction to splicing mechanism is discussed along with self splicing mechanism is explained briefly in this session

Post-transciptional modifications- RNA Splicing

Spliceosome mediated mechanism is discussed in detail in this session

Post-transciptional modifications- RNA splicing 2

Alternative splicing with an example is discussed continued with trans-splicing mechanism is also briefly discussed

Post-transciptional modifications-Alternative RNA Splicing

Processing of pre rRNA and pre tRNA to mature rRNA and tRNA is discussed in detail

Processing of pre-rRNA and pre-tRNA

Role of transcription factors, activators , co -activators(proteins), Long range elements (enhancers, insulators and LCR- DNA sequences) are discussed briefly in this session

Role of transcription factors in Eukaryotes

Degradation of mRNA is discussed in this session

Degradation of mRNA

An Introduction to mRNA interference is discussed in this session. I regret the inconvenience for audio quality

MRNA Interference- Introduction

Process of mirna mediated mRNA Interference

MRNA interference- miRNA

SiRNA and shRNA is discussed in detail. Comparison between miRNA siRNA and shRNA is also discussed in this session

MRNA interference- siRNA and shRNA

Brief introduction on protein synthesis along with the requirements and phases involved in protein synthesis is discussed in this session

Protein synthesis- Introduction

An brief overview of protein synthesis is discussed . The first phase- activation of amino acids is discussed bin detail in this session

Activation of amino acid

Initiation process -formation of 70s complex in prokaryotes is explained briefly in this session

Prokaryotic translation- initiation

Elongation process in prokaryotes is briefly discussed

Prokaryotic translation- Elongation

Termination process along with release factors is discussed in this session

Prokaryotic translation- termination

Protein synthesis in eukaryotes is briefly discussed with the initiation phase discussed in detail

Protein synthesis- Eukaryotes

Post translational modifications- various chemical  modifications are explained in detail

Post-translational modifications

Various antibiotics inhibiting the process of transcription and translation are discussed along the tabular column . Types of mRNA is also shown using table format

Inhibitors of biological processes

Lac operon- structural genes, mechanism of inducible system is discussed in detail

Gene regulation in prokaryotes

Trp operon- structural genes , attenuator sequence is explained in detail

Gene Regulation in prokaryotes-2

Gene regulation in Eukaryotes- short note on TF and distal elements . Brief discussion on histones, histone acetylation, deacetylation and methylation

Gene Regulation in Eukaryotes

Reverse transcription process is explained in detail in this session

Reverse transcription

Transport of RNA via Ran GTP mechanism is discussed in this session

RNA transport

Discussion on do's and dont's while preparing for the exam also simple strategy to help with the preparation is briefly discussed in this session

Simple strategy to crack CSIR-UGCNET

Author of Book- Mind Maps for Life Sciences, Qualified CSIR-NET,GATE XL,BT, REET, MPAT 2 times Rank 1, Guided  30k+ Students

Neha Taneja

In this course, there is a detailed description about trptophan operon and it's regulation. Practice questions and CSIR-NET previous year questions will remain the main highlights after completion of the theoretical part.

Tryptophan Operon: CSIR UGC NET

This course includes explanation about lac operon, which is a operon required for the transport and metabolism of lactose in Escherichia coli and many other enteric bacteria. Proper diagrammatic representations has been used for better understanding.

Lac Operon : Gene Regulation in Bacteria - CSIR-UGC NET

This course includes explanation about lac operon that basically helps in controlling the gene expression in prokaryotes. This operon required the transport and metabolism in Escherichia coli and many other enteric bacteria.

(Hindi) Lac Operon - Gene Regulation in Bacteria : CSIR-UGC NET

In this course, there is a detailed description about tryptophan operon and it’s regulation. Practice questions and CSIR previous year question will remain the main highlights after completion of the theoretical part.

(Hindi) Tryptophan (Trp) Operon : CSIR-UGC NET

Dr.  Sashi Prabha, Assistant professor. Did PhD from Andhra unversity, department  of Microbiology. Have 14 years teaching experience.

Sashi Prabha Muddada

In this course, the educator is discussing the transcription of DNA, the difference between  DNA & RNA.  Enzymes involved in transcription for CSIR-UGC NET aspirants

Lessons

52 lessons • 11h 37m