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Cardiovascular and Renal Systems

Quick practice

Question 1 of 5

The positive inotropic effect of digitalis is due to inhibition of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to?

A

Decreased efflux of Na+ leading to less negative resting membrane potential and opening of voltage gated Ca++ channels on the T tubules.

B

Increased intracellular Na+ decreasing the activity of Ca++ pump in the sarcoplasmic reticulum.

C

Increased intracellular Na+ causing increased efflux of Na+ and increased infl ux of Ca++ through Na+/Ca++ exchanger in the sarcolemma.

D

Decreased activity of Na+/Ca++ exchanger causing decreased influx of sodium and decreased efflux of Ca++ in the sarcolemma.

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