A 34-year-old man comes to OPD because of a 3-month history of progressively worsening shortness of breath on exertion. He is concerned that he has asthma and would like to be started on albuterol. Which of the following findings is most likely to indicate a different diagnosis in this patient?
Inspiratory : expiratory ratio of 1:3 on auscultation
129% of the predicted diffusion capacity of the lung for carbon monoxide
Decrease in FEV; by 6% after administration of high-dose methacholine
Bipyramidal crystals measuring 50 um on sputum analysis
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