A 45 year-old homeless female is found unconscious in the street. Her urine drug screen is positive for heroin. She is febrile and when she awakes she notes that she has been having problems with chest pain, shortness of breath and a cough. Physical exam reveals a high-pitched holosystolic murmur heard best at the apex, dark red lesions in the nailbeds and diffuse petechiae. Histology of her damaged heart valve would most likely show which of the following?
Clumps of fibrin on the valvular leaflet
Predominantly eosinophilic and monocytic infiltrate
Bacterial invasion with a predominantly neutrophilic response
Non-necrotizing granulomas and giant cells
Coagulative necrosis with nuclear pyknosis
Boost your performance with adaptive practice tests
Practice every concept in the syllabus
Compare your speed and accuracy with your peers
Download the app and practice on the go