It is the property of our immune system to discriminate between the self and non-self cells. A patient suffering from a disease when observed found that there is no generation of the antibodies against the antigen present in his body. This is possible because:
the antibodies are not active in the patient’s body
the antigen is composed of protein molecules like collagen and cytochrome-C
the observation made was wrong as the antibodies were present against the antigen
the antigen does not carry epitope on its surface which is recognized by the antibodies
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